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Whole transcriptome RNA-Seq allelic expression in human brain
BACKGROUND: Measuring allelic RNA expression ratios is a powerful approach for detecting cis-acting regulatory variants, RNA editing, loss of heterozygosity in cancer, copy number variation, and allele-specific epigenetic gene silencing. Whole transcriptome RNA sequencing (RNA-Seq) has emerged as a...
Autores principales: | Smith, Ryan M, Webb, Amy, Papp, Audrey C, Newman, Leslie C, Handelman, Samuel K, Suhy, Adam, Mascarenhas, Roshan, Oberdick, John, Sadee, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765493/ https://www.ncbi.nlm.nih.gov/pubmed/23968248 http://dx.doi.org/10.1186/1471-2164-14-571 |
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