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Phospholipase D regulates the size of skeletal muscle cells through the activation of mTOR signaling

mTOR is a major actor of skeletal muscle mass regulation in situations of atrophy or hypertrophy. It is established that Phospholipase D (PLD) activates mTOR signaling, through the binding of its product phosphatidic acid (PA) to mTOR protein. An influence of PLD on muscle cell size could thus be su...

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Detalles Bibliográficos
Autores principales: Jaafar, Rami, De Larichaudy, Joffrey, Chanon, Stéphanie, Euthine, Vanessa, Durand, Christine, Naro, Fabio, Bertolino, Philippe, Vidal, Hubert, Lefai, Etienne, Némoz, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765503/
https://www.ncbi.nlm.nih.gov/pubmed/23915343
http://dx.doi.org/10.1186/1478-811X-11-55