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Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy

BACKGROUND: Diabetes is associated with a high incidence of macrovascular disease (MVD), including peripheral and coronary artery disease. Circulating soluble-Klotho (sKlotho) is produced in the kidney and is a putative anti-aging and vasculoprotective hormone. Reduced Klotho levels may therefore in...

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Detalles Bibliográficos
Autores principales: van Ark, Joris, Hammes, Hans-Peter, van Dijk, Marcory C R F, Vervloet, Marc G, Wolffenbuttel, Bruce H R, van Goor, Harry, Hillebrands, Jan-Luuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765553/
https://www.ncbi.nlm.nih.gov/pubmed/23945089
http://dx.doi.org/10.1186/1475-2840-12-116