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Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy
BACKGROUND: Diabetes is associated with a high incidence of macrovascular disease (MVD), including peripheral and coronary artery disease. Circulating soluble-Klotho (sKlotho) is produced in the kidney and is a putative anti-aging and vasculoprotective hormone. Reduced Klotho levels may therefore in...
Autores principales: | van Ark, Joris, Hammes, Hans-Peter, van Dijk, Marcory C R F, Vervloet, Marc G, Wolffenbuttel, Bruce H R, van Goor, Harry, Hillebrands, Jan-Luuk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765553/ https://www.ncbi.nlm.nih.gov/pubmed/23945089 http://dx.doi.org/10.1186/1475-2840-12-116 |
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