Platelet-derived growth factor B induces senescence and transformation in normal human fibroblasts

Normal cells enter a senescent state upon aberrant oncogenic signals and this response inhibits tumor initiation and progression. It is now well admitted that intracellular and membrane localized oncogenes can illicit oncogene induced senescence. However, the effect of mitogenic growth factor on cel...

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Detalles Bibliográficos
Autores principales: Vindrieux, David, Gras, Baptiste, Garcia-Belinchon, Merce, Mourah, Samia, Lebbe, Céleste, Augert, Arnaud, Bernard, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765581/
https://www.ncbi.nlm.nih.gov/pubmed/23934686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765581/
https://www.ncbi.nlm.nih.gov/pubmed/23934686

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