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Enhanced levels of asymmetric dimethylarginine in a serum of middle age patients with myelodysplastic syndrome

Myelodysplastic syndromes (MDS) are hematological malignancies of unclear etiology where oxidative stress may contribute to the pathogenesis. Methylarginines, naturally occurring inhibitors of NO synthase, can increase superoxide generation from uncoupled NO synthase. We found significant increase i...

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Detalles Bibliográficos
Autores principales: Štikarová, Jana, Suttnar, Jiří, Pimková, Kristýna, Chrastinová-Mášová, Leona, Čermák, Jaroslav, Dyr, Jan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765587/
https://www.ncbi.nlm.nih.gov/pubmed/23958336
http://dx.doi.org/10.1186/1756-8722-6-58