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The effect of simvastatin on lipid droplets accumulation in human embryonic kidney cells and pancreatic cancer cells

BACKGROUND: Statins (HMG-CoA reductase inhibitors) represent a major class of compounds for the treatment of hypercholesterolemia due to their ability to inhibit de novo cholesterol synthesis. In addition to their hypolipidemic effects, chemoprotective properties have been attributed to statins as w...

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Detalles Bibliográficos
Autores principales: Gbelcová, Helena, Švéda, Martin, Laubertová, Lucia, Varga, Ivan, Vítek, Libor, Kolář, Michal, Strnad, Hynek, Zelenka, Jaroslav, Böhmer, Daniel, Ruml, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765626/
https://www.ncbi.nlm.nih.gov/pubmed/23961716
http://dx.doi.org/10.1186/1476-511X-12-126