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Nitric oxide modulates the hyperalgesic response to mechanical noxious stimuli in sleep-deprived rats
BACKGROUND: Sleep restriction alters pain perception in animals and humans, and many studies have indicated that paradoxical sleep deprivation (PSD) promotes hyperalgesia. The hyperalgesia observed after mechanical nociceptive stimulus is reversed through nitric oxide synthase (NOS) inhibition. Both...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765713/ https://www.ncbi.nlm.nih.gov/pubmed/23987566 http://dx.doi.org/10.1186/1471-2202-14-92 |