Nitric oxide modulates the hyperalgesic response to mechanical noxious stimuli in sleep-deprived rats

BACKGROUND: Sleep restriction alters pain perception in animals and humans, and many studies have indicated that paradoxical sleep deprivation (PSD) promotes hyperalgesia. The hyperalgesia observed after mechanical nociceptive stimulus is reversed through nitric oxide synthase (NOS) inhibition. Both...

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Detalles Bibliográficos
Autores principales: Damasceno, Fabio, Skinner, Gabriela O, Araújo, Paulo C, Ferraz, Marcia MD, Tenório, Frank, de Almeida, Olga MMS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765713/
https://www.ncbi.nlm.nih.gov/pubmed/23987566
http://dx.doi.org/10.1186/1471-2202-14-92

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