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Expression of metallothionein and Nrf2 pathway genes in lung cancer and cancer-surrounding tissues

BACKGROUND: Nuclear factor (erythroid-derived 2)-like (Nrf)2 and metallothionein have been implicated in carcinogenesis. This study investigated the expression of Nrf2 and of Nrf2-targeted genes (NQO1 and GCLC) and the genes for the metallothionein (MT) isoforms (MT-1A and MT-2A) in human lung cance...

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Detalles Bibliográficos
Autores principales: Liang, Gui-You, Lu, Sheng-Xun, Xu, Gang, Liu, Xing-Da, Li, Jian, Zhang, Deng-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765715/
https://www.ncbi.nlm.nih.gov/pubmed/23947958
http://dx.doi.org/10.1186/1477-7819-11-199