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Rule–based regulatory and metabolic model for Quorum sensing in P. aeruginosa

BACKGROUND: In the pathogen P. aeruginosa, the formation of virulence factors is regulated via Quorum sensing signaling pathways. Due to the increasing number of strains that are resistant to antibiotics, there is a high interest to develop novel antiinfectives. In the combat of resistant bacteria,...

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Detalles Bibliográficos
Autores principales: Schaadt, Nadine S, Steinbach, Anke, Hartmann, Rolf W, Helms, Volkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765737/
https://www.ncbi.nlm.nih.gov/pubmed/23965312
http://dx.doi.org/10.1186/1752-0509-7-81