Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma

BACKGROUND: Prevalence and distribution of pathogenetic mutations in BRAF and NRAS genes were evaluated in multiple melanoma lesions from patients with different geographical origin within the same Italian population. METHODS: Genomic DNA from a total of 749 tumor samples (451 primary tumors and 298...

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Detalles Bibliográficos
Autores principales: Colombino, Maria, Lissia, Amelia, Capone, Mariaelena, De Giorgi, Vincenzo, Massi, Daniela, Stanganelli, Ignazio, Fonsatti, Ester, Maio, Michele, Botti, Gerardo, Caracò, Corrado, Mozzillo, Nicola, Ascierto, Paolo A, Cossu, Antonio, Palmieri, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765741/
https://www.ncbi.nlm.nih.gov/pubmed/23987572
http://dx.doi.org/10.1186/1479-5876-11-202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765741/
https://www.ncbi.nlm.nih.gov/pubmed/23987572
http://dx.doi.org/10.1186/1479-5876-11-202

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