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MethyQA: a pipeline for bisulfite-treated methylation sequencing quality assessment

BACKGROUND: DNA methylation is an epigenetic event that adds a methyl-group to the 5’ cytosine. This epigenetic modification can significantly affect gene expression in both normal and diseased cells. Hence, it is important to study methylation signals at the single cytosine site level, which is now...

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Detalles Bibliográficos
Autores principales: Sun, Shuying, Noviski, Aaron, Yu, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765750/
https://www.ncbi.nlm.nih.gov/pubmed/23968174
http://dx.doi.org/10.1186/1471-2105-14-259