Pyocyanin-induced mucin production is associated with redox modification of FOXA2

BACKGROUND: The redox-active pyocyanin (PCN) is a toxic, secondary metabolite secreted by the respiratory pathogen Pseudomonas aeruginosa (PA). Previously, we have shown that mouse lungs chronically exposed to PCN develop goblet cell hyperplasia and metaplasia (GCHM) and mucus hypersecretion, fibros...

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Detalles Bibliográficos
Autores principales: Hao, Yonghua, Kuang, Zhizhou, Xu, Ying, Walling, Brent E, Lau, Gee W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765780/
https://www.ncbi.nlm.nih.gov/pubmed/23915402
http://dx.doi.org/10.1186/1465-9921-14-82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765780/
https://www.ncbi.nlm.nih.gov/pubmed/23915402
http://dx.doi.org/10.1186/1465-9921-14-82

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