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Functional Val66Met polymorphism of Brain-derived neurotrophic factor in type 2 diabetes with depression in Han Chinese subjects

BACKGROUND: Brain-derived neurotrophic factor (BDNF) has been implicated in the pathogenesis of major depression. Individuals with type 2 diabetes (T2DM) have a high prevalence of major depression and low levels of BDNF. We therefore explored whether the BDNF Val66Met polymorphism is associated with...

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Detalles Bibliográficos
Autores principales: Zhou, Jian-Xin, Li, He-Chao, Bai, Xue-Jun, Chang, Bao-Cheng, Li, Chun-Jun, Sun, Pei, Chen, Li-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765870/
https://www.ncbi.nlm.nih.gov/pubmed/23968401
http://dx.doi.org/10.1186/1744-9081-9-34