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Identification of a novel infection-enhancing epitope on dengue prM using a dengue cross-reacting monoclonal antibody
BACKGROUND: Dengue virus (DENV) infection is the most important arthropod- borne viral disease in human, but antiviral therapy and approved vaccines remain unavailable due to antibody-dependent enhancement (ADE) phenomenon. Many studies showed that pre-membrane (prM)-specific antibodies do not effic...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765915/ https://www.ncbi.nlm.nih.gov/pubmed/23987307 http://dx.doi.org/10.1186/1471-2180-13-194 |