Knockout of TLR4 and TLR2 impair the nerve regeneration by delayed demyelination but not remyelination

BACKGROUND: Knockout of either toll-like receptor 4 (TLR4) or 2 (TLR2) had been reported to delay the Wallerian degeneration after peripheral nerve injury by deterring the recruitment of the macrophages and clearance of myelin debris. However, the impact on the remyelination process is poorly unders...

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Detalles Bibliográficos
Autores principales: Wu, Shao-Chun, Rau, Cheng-Shyuan, Lu, Tsu-Hsiang, Wu, Chia-Jung, Wu, Yi-Chan, Tzeng, Siou-Ling, Chen, Yi-Chun, Hsieh, Ching-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765918/
https://www.ncbi.nlm.nih.gov/pubmed/23984978
http://dx.doi.org/10.1186/1423-0127-20-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765918/
https://www.ncbi.nlm.nih.gov/pubmed/23984978
http://dx.doi.org/10.1186/1423-0127-20-62

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