Cargando…

Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

Renal cell carcinoma (RCC), the most common malignancy of the kidney, is refractory to standard therapy and has an incidence that continues to rise. Screening of plant extracts in search of new agents to treat RCC resulted in the discovery of englerin A (EA), a natural product exhibiting potent sele...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Richard T, Yu, Alice L, Diccianni, Mitchell B, Theodorakis, Emmanuel A, Batova, Ayse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765946/
https://www.ncbi.nlm.nih.gov/pubmed/23958461
http://dx.doi.org/10.1186/1756-9966-32-57