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Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression
BACKGROUND: Histone deacetylases (HDACs) play a critical role in the maintenance of genome stability. Class I HDACs, histone deacetylase 1 and 2 (Hdac1 and Hdac2) are recruited to the replication fork by virtue of their interactions with the replication machinery. However, functions for Hdac1 and Hd...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765969/ https://www.ncbi.nlm.nih.gov/pubmed/23947532 http://dx.doi.org/10.1186/1756-8935-6-27 |