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High rate of spontaneous inhibitor clearance during the long term observation study of a single cohort of 524 haemophilia A patients not undergoing immunotolerance

BACKGROUND: The natural history of inhibitors in patients with haemophilia A not undergoing immune tolerance induction (ITI) is largely unknown. A recent randomized controlled trial suggests that the higher the FVIII dose used for ITI, the faster the clearance and the lower the rate of bleeding, wit...

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Detalles Bibliográficos
Autores principales: Tagariello, Giuseppe, Iorio, Alfonso, Matino, Davide, Belvini, Donata, Salviato, Roberta, Sartori, Roberto, Radossi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766100/
https://www.ncbi.nlm.nih.gov/pubmed/24001010
http://dx.doi.org/10.1186/1756-8722-6-63