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Target of rapamycin signaling regulates high mobility group protein association to chromatin, which functions to suppress necrotic cell death

BACKGROUND: The target of rapamycin complex 1 (TORC1) is an evolutionarily conserved signal transduction pathway activated by environmental nutrients that regulates gene transcription to control cell growth and proliferation. How TORC1 modulates chromatin structure to control gene expression, howeve...

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Detalles Bibliográficos
Autores principales: Chen, Hongfeng, Workman, Jason J, Tenga, Alexa, Laribee, R Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766136/
https://www.ncbi.nlm.nih.gov/pubmed/24044743
http://dx.doi.org/10.1186/1756-8935-6-29