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MicroRNA profiling implicates the insulin-like growth factor pathway in bleomycin-induced pulmonary fibrosis in mice

BACKGROUND: Idiopathic pulmonary fibrosis is a disease characterized by alveolar epithelial cell injury, inflammatory cell infiltration and deposition of extracellular matrix in lung tissue. As mouse models of bleomycin-induced pulmonary fibrosis display many of the same phenotypes observed in patie...

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Detalles Bibliográficos
Autores principales: Honeyman, Lisa, Bazett, Mark, Tomko, Tomasz G, Haston, Christina K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766165/
https://www.ncbi.nlm.nih.gov/pubmed/23987664
http://dx.doi.org/10.1186/1755-1536-6-16