Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are neurodegenerative disorders that are characterized by cytoplasmic aggregates and nuclear clearance of TAR DNA-binding protein 43 (TDP-43). Studies in Drosophila, zebrafish and mouse demonstrate that the neuronal dys...

Descripción completa

Detalles Bibliográficos
Autores principales: Diaper, Danielle C., Adachi, Yoshitsugu, Lazarou, Luke, Greenstein, Max, Simoes, Fabio A., Di Domenico, Angelique, Solomon, Daniel A., Lowe, Simon, Alsubaie, Rawan, Cheng, Daryl, Buckley, Stephen, Humphrey, Dickon M., Shaw, Christopher E., Hirth, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766182/
https://www.ncbi.nlm.nih.gov/pubmed/23727833
http://dx.doi.org/10.1093/hmg/ddt243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766182/
https://www.ncbi.nlm.nih.gov/pubmed/23727833
http://dx.doi.org/10.1093/hmg/ddt243

Ejemplares similares