Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen

BACKGROUND: Guanylate Cyclase C (GC-C) is an apically-oriented transmembrane receptor that is expressed on epithelial cells of the intestine. Activation of GC-C by the endogenous ligands guanylin or uroguanylin elevates intracellular cGMP and is implicated in intestinal ion secretion, cell prolifera...

Descripción completa

Detalles Bibliográficos
Autores principales: Mann, Elizabeth A, Harmel-Laws, Eleana, Cohen, Mitchell B, Steinbrecher, Kris A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766218/
https://www.ncbi.nlm.nih.gov/pubmed/24004613
http://dx.doi.org/10.1186/1471-230X-13-135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766218/
https://www.ncbi.nlm.nih.gov/pubmed/24004613
http://dx.doi.org/10.1186/1471-230X-13-135

Ejemplares similares