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MC1R genotype as a predictor of early-onset melanoma, compared with self-reported and physician-measured traditional risk factors: an Australian case-control-family study

BACKGROUND: Melanocortin-1 receptor (MC1R) gene variants are very common and are associated with melanoma risk, but their contribution to melanoma risk prediction compared with traditional risk factors is unknown. We aimed to 1) evaluate the separate and incremental contribution of MC1R genotype to...

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Detalles Bibliográficos
Autores principales: Cust, Anne E, Goumas, Chris, Vuong, Kylie, Davies, John R, Barrett, Jennifer H, Holland, Elizabeth A, Schmid, Helen, Agha-Hamilton, Chantelle, Armstrong, Bruce K, Kefford, Richard F, Aitken, Joanne F, Giles, Graham G, Bishop, D Timothy, Newton-Bishop, Julia A, Hopper, John L, Mann, Graham J, Jenkins, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766240/
https://www.ncbi.nlm.nih.gov/pubmed/24134749
http://dx.doi.org/10.1186/1471-2407-13-406