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Global differences in specific histone H3 methylation are associated with overweight and type 2 diabetes

BACKGROUND: Epidemiological evidence indicates yet unknown epigenetic mechanisms underlying a propensity for overweight and type 2 diabetes. We analyzed the extent of methylation at lysine 4 and lysine 9 of histone H3 in primary human adipocytes from 43 subjects using modification-specific antibodie...

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Detalles Bibliográficos
Autores principales: Jufvas, Åsa, Sjödin, Simon, Lundqvist, Kim, Amin, Risul, Vener, Alexander V, Strålfors, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766271/
https://www.ncbi.nlm.nih.gov/pubmed/24004477
http://dx.doi.org/10.1186/1868-7083-5-15