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Global differences in specific histone H3 methylation are associated with overweight and type 2 diabetes
BACKGROUND: Epidemiological evidence indicates yet unknown epigenetic mechanisms underlying a propensity for overweight and type 2 diabetes. We analyzed the extent of methylation at lysine 4 and lysine 9 of histone H3 in primary human adipocytes from 43 subjects using modification-specific antibodie...
Autores principales: | Jufvas, Åsa, Sjödin, Simon, Lundqvist, Kim, Amin, Risul, Vener, Alexander V, Strålfors, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766271/ https://www.ncbi.nlm.nih.gov/pubmed/24004477 http://dx.doi.org/10.1186/1868-7083-5-15 |
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