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Genetic control of murine invariant natural killer T-cells maps to multiple type 1 diabetes regions
Reduced frequency of invariant natural killer T (iNKT)-cells has been indicated as a contributing factor to type 1 diabetes (T1D) development in NOD mice. To further understand the genetic basis of the defect, we generated (NOD X ICR)F2 mice to map genes that control iNKT-cell development. We determ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766462/ https://www.ncbi.nlm.nih.gov/pubmed/23719031 http://dx.doi.org/10.1038/gene.2013.32 |