Cargando…

Comparative Analysis of Context-Dependent Mutagenesis Using Human and Mouse Models

Substitution rates strongly depend on their nucleotide context. One of the most studied examples is the excess of C > T mutations in the CG context in various groups of organisms, including vertebrates. Studies on the molecular mechanisms underlying this mutation regularity have provided insights...

Descripción completa

Detalles Bibliográficos
Autores principales: Medvedeva, Sofya A., Panchin, Alexander Y., Alexeevski, Andrey V., Spirin, Sergey A., Panchin, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766559/
https://www.ncbi.nlm.nih.gov/pubmed/24058920
http://dx.doi.org/10.1155/2013/989410