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Comparative Analysis of Context-Dependent Mutagenesis Using Human and Mouse Models
Substitution rates strongly depend on their nucleotide context. One of the most studied examples is the excess of C > T mutations in the CG context in various groups of organisms, including vertebrates. Studies on the molecular mechanisms underlying this mutation regularity have provided insights...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766559/ https://www.ncbi.nlm.nih.gov/pubmed/24058920 http://dx.doi.org/10.1155/2013/989410 |