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Enhanced Topical Delivery of Tetrandrine by Ethosomes for Treatment of Arthritis

The purpose of this work was to explore the feasibility of ethosomes for improving the antiarthritic efficacy of tetrandrine by topical application. It was found that tetrandrine was a weak base (pK (a) = 7.06) with pH-dependent partition coefficient. The spherical-shaped ethosomes were prepared by...

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Detalles Bibliográficos
Autores principales: Fan, Chao, Li, Xinru, Zhou, Yanxia, Zhao, Yong, Ma, Shujin, Li, Wenjing, Liu, Yan, Li, Guiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766603/
https://www.ncbi.nlm.nih.gov/pubmed/24062995
http://dx.doi.org/10.1155/2013/161943