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Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells

BACKGROUND: Matrix metalloproteases and collagen are key participants in breast cancer, but their precise roles in cancer etiology and progression remain unclear. MMP13 helps regulate collagen structure and has been ascribed largely harmful roles in cancer, but some studies demonstrate that MMP13 ma...

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Detalles Bibliográficos
Autores principales: Perry, Seth W, Schueckler, Jill M, Burke, Kathleen, Arcuri, Giuseppe L, Brown, Edward B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766650/
https://www.ncbi.nlm.nih.gov/pubmed/24010522
http://dx.doi.org/10.1186/1471-2407-13-411