Molecular crosstalk between apoptosis and autophagy induced by a novel 2-methoxyestradiol analogue in cervical adenocarcinoma cells

BACKGROUND: 2-Methoxyestradiol has been shown to induce both autophagy and apoptosis in various carcinogenic cell lines. Although a promising anti-cancer agent, it has poor bioavailability and rapid in vivo metabolism which decreases its efficiency. In order to improve 2-methoxyestradiol’s anti-prol...

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Detalles Bibliográficos
Autores principales: Theron, Anne E, Nolte, Elsie M, Lafanechère, Laurence, Joubert, Annie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766685/
https://www.ncbi.nlm.nih.gov/pubmed/23977838
http://dx.doi.org/10.1186/1475-2867-13-87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766685/
https://www.ncbi.nlm.nih.gov/pubmed/23977838
http://dx.doi.org/10.1186/1475-2867-13-87

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