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Healthy ageing and depletion of intracellular glutathione influences T cell membrane thioredoxin-1 levels and cytokine secretion

BACKGROUND: During ageing an altered redox balance has been observed in both intracellular and extracellular compartments, primarily due to glutathione depletion and metabolic stress. Maintaining redox homeostasis is important for controlling proliferation and apoptosis in response to specific stimu...

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Detalles Bibliográficos
Autores principales: Carilho Torrao, Rita Barreto Duarte, Dias, Irundika HK, Bennett, Stuart J, Dunston, Christopher R, Griffiths, Helen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766689/
https://www.ncbi.nlm.nih.gov/pubmed/24007191
http://dx.doi.org/10.1186/1752-153X-7-150