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Rapid emergence of a virulent PB2 E627K variant during adaptation of highly pathogenic avian influenza H7N7 virus to mice

BACKGROUND: Highly pathogenic avian influenza (HPAI) viruses pose a potential human health threat as they can be transmitted directly from infected poultry to humans. During a large outbreak of HPAI H7N7 virus among poultry in The Netherlands in 2003, bird to human transmission was confirmed in 89 c...

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Detalles Bibliográficos
Autores principales: de Jong, Rineke MC, Stockhofe-Zurwieden, Norbert, Verheij, Eline S, de Boer-Luijtze, Els A, Ruiter, Saskia JM, de Leeuw, Olav S, Cornelissen, Lisette AHM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766704/
https://www.ncbi.nlm.nih.gov/pubmed/24007444
http://dx.doi.org/10.1186/1743-422X-10-276