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The Importance of Myeloperoxidase in Apocynin-Mediated NADPH Oxidase Inhibition

Apocynin is widely used as an inhibitor of the NADPH oxidase. Since myeloperoxidase (MPO) has been considered as essential for the mechanism of action of apocynin, here we used cells with different levels of MPO and compared their sensitivity to apocynin. HL-60 cells were differentiated with DMSO or...

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Detalles Bibliográficos
Autores principales: de Almeida, Ana Carolina, dos Santos Vilela, Maria Marluce, Condino-Neto, Antonio, Ximenes, Valdecir F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767205/
https://www.ncbi.nlm.nih.gov/pubmed/24049643
http://dx.doi.org/10.5402/2012/260453