Comparison of anti-EGFR-Fab’ conjugated immunoliposomes modified with two different conjugation linkers for siRNa delivery in SMMC-7721 cells

BACKGROUND: Targeted liposome-polycation-DNA complex (LPD), mainly conjugated with antibodies using functionalized PEG derivatives, is an effective nanovector for systemic delivery of small interference RNA (siRNA). However, there are few studies reporting the effect of different conjugation linkers...

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Detalles Bibliográficos
Autores principales: Deng, Li, Zhang, Yingying, Ma, Lulu, Jing, Xiaolong, Ke, Xingfa, Lian, Jianhao, Zhao, Qiang, Yan, Bo, Zhang, Jinfeng, Yao, Jianzhong, Chen, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767494/
https://www.ncbi.nlm.nih.gov/pubmed/24023515
http://dx.doi.org/10.2147/IJN.S47597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767494/
https://www.ncbi.nlm.nih.gov/pubmed/24023515
http://dx.doi.org/10.2147/IJN.S47597

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