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Comparison of anti-EGFR-Fab’ conjugated immunoliposomes modified with two different conjugation linkers for siRNa delivery in SMMC-7721 cells
BACKGROUND: Targeted liposome-polycation-DNA complex (LPD), mainly conjugated with antibodies using functionalized PEG derivatives, is an effective nanovector for systemic delivery of small interference RNA (siRNA). However, there are few studies reporting the effect of different conjugation linkers...
Autores principales: | Deng, Li, Zhang, Yingying, Ma, Lulu, Jing, Xiaolong, Ke, Xingfa, Lian, Jianhao, Zhao, Qiang, Yan, Bo, Zhang, Jinfeng, Yao, Jianzhong, Chen, Jianming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767494/ https://www.ncbi.nlm.nih.gov/pubmed/24023515 http://dx.doi.org/10.2147/IJN.S47597 |
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