Antigen-Specific Suppression and Immunological Synapse Formation by Regulatory T Cells Require the Mst1 Kinase

Although the cell-to-cell contact between CD4(+)Foxp3(+) regulatory T (Treg) and their target cells is important for the suppressor function of Treg cells, the regulation of this process is not well understood. Here we show that the Mst1 kinase plays a critical role in the suppressor function of Tre...

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Detalles Bibliográficos
Autores principales: Tomiyama, Takashi, Ueda, Yoshihiro, Katakai, Tomoya, Kondo, Naoyuki, Okazaki, Kazuichi, Kinashi, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767606/
https://www.ncbi.nlm.nih.gov/pubmed/24040101
http://dx.doi.org/10.1371/journal.pone.0073874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767606/
https://www.ncbi.nlm.nih.gov/pubmed/24040101
http://dx.doi.org/10.1371/journal.pone.0073874

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