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Suramin: A Potential Therapy for Diabetic Nephropathy

OBJECTIVE: To determine whether delayed administration of a single dose of suramin, a drug that has been used extensively in humans to treat trypanosomiasis, attenuates renal injury in a leptin receptor deficient C57BLKS/J db/db type 2 diabetic nephropathy (T2DN) mouse model. RESEARCH DESIGN AND MET...

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Detalles Bibliográficos
Autores principales: Korrapati, Midhun C., Howell, Lauren H., Shaner, Brooke E., Megyesi, Judit K., Siskind, Leah J., Schnellmann, Rick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767615/
https://www.ncbi.nlm.nih.gov/pubmed/24040012
http://dx.doi.org/10.1371/journal.pone.0073655