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Structural and Functional Implication of RAP80 ΔGlu81 Mutation

Receptor Associated Protein 80 (RAP80) is a member of RAP80-BRCA1-CCDC98 complex family and helps in its recruitment to the DNA damage site for effective homologous recombination repair. It encompasses two tandem UIMs (UIM1 and UIM2) motif at its N-terminus, which interact with K-63 linked polyubiqu...

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Detalles Bibliográficos
Autores principales: Vikrant, Kumar, Rajan, Yadav, Lumbini R., Nakhwa, Pallavi, Waghmare, Sanjeev K., Goyal, Peyush, Varma, Ashok K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767628/
https://www.ncbi.nlm.nih.gov/pubmed/24039796
http://dx.doi.org/10.1371/journal.pone.0072707