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Integrin-Specific Control of Focal Adhesion Kinase and RhoA Regulates Membrane Protrusion and Invasion

Cell invasion through extracellular matrix (ECM) is a hallmark of the metastatic cascade. Cancer cells require adhesion to surrounding tissues for efficient migration to occur, which is mediated through the integrin family of receptors. Alterations in expression levels of β1 and β3 integrins have pr...

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Detalles Bibliográficos
Autores principales: Costa, Patricia, Scales, Tim M. E., Ivaska, Johanna, Parsons, Maddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767638/
https://www.ncbi.nlm.nih.gov/pubmed/24040310
http://dx.doi.org/10.1371/journal.pone.0074659