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Integrin-Specific Control of Focal Adhesion Kinase and RhoA Regulates Membrane Protrusion and Invasion
Cell invasion through extracellular matrix (ECM) is a hallmark of the metastatic cascade. Cancer cells require adhesion to surrounding tissues for efficient migration to occur, which is mediated through the integrin family of receptors. Alterations in expression levels of β1 and β3 integrins have pr...
Autores principales: | Costa, Patricia, Scales, Tim M. E., Ivaska, Johanna, Parsons, Maddy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767638/ https://www.ncbi.nlm.nih.gov/pubmed/24040310 http://dx.doi.org/10.1371/journal.pone.0074659 |
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