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NMR Structure of Temporin-1 Ta in Lipopolysaccharide Micelles: Mechanistic Insight into Inactivation by Outer Membrane

BACKGROUND: Antimicrobial peptides (AMPs) play important roles in the innate defense mechanism. The broad spectrum of activity of AMPs requires an efficient permeabilization of the bacterial outer and inner membranes. The outer leaflet of the outer membrane of Gram negative bacteria is made of a spe...

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Detalles Bibliográficos
Autores principales: Saravanan, Rathi, Joshi, Mangesh, Mohanram, Harini, Bhunia, Anirban, Mangoni, Maria Luisa, Bhattacharjya, Surajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767682/
https://www.ncbi.nlm.nih.gov/pubmed/24039798
http://dx.doi.org/10.1371/journal.pone.0072718