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Nanodiscs Allow Phage Display Selection for Ligands to Non-Linear Epitopes on Membrane Proteins
In this work, we exploited a method that uses polytopic membrane proteins as targets for phage display selections. Membrane proteins represent the largest class of drug targets and drug discovery is mostly based on the identification of ligands binding to target molecules. The screening of a phage d...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767683/ https://www.ncbi.nlm.nih.gov/pubmed/24039747 http://dx.doi.org/10.1371/journal.pone.0072272 |