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Aluminum Hydroxide Adjuvant Differentially Activates the Three Complement Pathways with Major Involvement of the Alternative Pathway
Al(OH)(3) is the most common adjuvant in human vaccines, but its mode of action remains poorly understood. Complement involvement in the adjuvant properties of Al(OH)(3) has been suggested in several reports together with a depot effect. It is here confirmed that Al(OH)(3) treatment of serum deplete...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767739/ https://www.ncbi.nlm.nih.gov/pubmed/24040248 http://dx.doi.org/10.1371/journal.pone.0074445 |