CTR1 Silencing Inhibits Angiogenesis by Limiting Copper Entry into Endothelial Cells

Increased levels of intracellular copper stimulate angiogenesis in human umbilical vein endothelial cells (HUVECs). Copper transporter 1 (CTR1) is a copper importer present in the cell membrane and plays a major role in copper transport. In this study, three siRNAs targeting CTR1 mRNA were designed...

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Detalles Bibliográficos
Autores principales: Narayanan, Gomathy, R., Bharathidevi S., Vuyyuru, Harish, Muthuvel, Bharathselvi, Konerirajapuram Natrajan, Sulochana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767743/
https://www.ncbi.nlm.nih.gov/pubmed/24039729
http://dx.doi.org/10.1371/journal.pone.0071982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767743/
https://www.ncbi.nlm.nih.gov/pubmed/24039729
http://dx.doi.org/10.1371/journal.pone.0071982

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