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SNP Detection in mRNA in Living Cells Using Allele Specific FRET Probes

Live mRNA detection allows real time monitoring of specific transcripts and genetic alterations. The main challenge of live genetic detection is overcoming the high background generated by unbound probes and reaching high level of specificity with minimal off target effects. The use of Fluorescence...

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Detalles Bibliográficos
Autores principales: Dahan, Liya, Huang, Lingyan, Kedmi, Ranit, Behlke, Mark A., Peer, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767744/
https://www.ncbi.nlm.nih.gov/pubmed/24039756
http://dx.doi.org/10.1371/journal.pone.0072389