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SNP Detection in mRNA in Living Cells Using Allele Specific FRET Probes
Live mRNA detection allows real time monitoring of specific transcripts and genetic alterations. The main challenge of live genetic detection is overcoming the high background generated by unbound probes and reaching high level of specificity with minimal off target effects. The use of Fluorescence...
Autores principales: | Dahan, Liya, Huang, Lingyan, Kedmi, Ranit, Behlke, Mark A., Peer, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767744/ https://www.ncbi.nlm.nih.gov/pubmed/24039756 http://dx.doi.org/10.1371/journal.pone.0072389 |
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