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PSMB9 Codon 60 Polymorphisms Have No Impact on the Activity of the Immunoproteasome Catalytic Subunit B1i Expressed in Multiple Types of Solid Cancer

The proteasome is a key regulator of cellular protein homeostasis and is a clinically validated anticancer target. The immunoproteasome, a subtype of proteasome expressed mainly in hematopoietic cells, was initially recognized for its role in antigen presentation during the immune response. Recently...

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Detalles Bibliográficos
Autores principales: Park, Ji Eun, Ao, Lin, Miller, Zachary, Kim, Kyungbo, Wu, Ying, Jang, Eun Ryoung, Lee, Eun Young, Kim, Kyung Bo, Lee, Wooin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767749/
https://www.ncbi.nlm.nih.gov/pubmed/24040045
http://dx.doi.org/10.1371/journal.pone.0073732