Long-Term Valproate Treatment Increases Brain Neuropeptide Y Expression and Decreases Seizure Expression in a Genetic Rat Model of Absence Epilepsy

The mechanisms by which valproate, one of the most widely prescribed anti-epileptic drugs, suppresses seizures have not been fully elucidated but may involve up-regulation of neuropeptide Y (NPY). We investigated the effects of valproate treatment in Genetic Absence Epilepsy Rats from Strasbourg (GA...

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Detalles Bibliográficos
Autores principales: Elms, Johanna, Powell, Kim L., van Raay, Leena, Dedeurwaerdere, Stefanie, O’Brien, Terence J., Morris, Margaret J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767750/
https://www.ncbi.nlm.nih.gov/pubmed/24039965
http://dx.doi.org/10.1371/journal.pone.0073505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767750/
https://www.ncbi.nlm.nih.gov/pubmed/24039965
http://dx.doi.org/10.1371/journal.pone.0073505

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